http://www.onlinepharmacycr.com/ RSS - News Feed www.onlinepharmacycr.com http://blogs.law.harvard.edu/tech/rss Jitbit RSS Feed Creator Tue, 13 Jan 2009 09:12:43 -0600 http://www.onlinepharmacycr.com/http://www.onlinepharmacycr.com/Warfarin has long been a highly effective drug therapy tool for doctors to prescribe to patients with stroke potential. The drug is also effective against venous thrombosis, but doctors are not sure how the drug should be properly managed. Only until recently, doctors have finally figured out the best dosages to benefit patients without prescribing too much. The study and findings have been published in an issue of Journal of Thrombosis and Haemostasis. The research that was published is data that was collected from almost four thousand patients. Each patient was given doses of warfarin to test the most effective dose.http://www.onlinepharmacycr.com/products/rss/RSS/index62.htmlTue, 13 Jan 2009 09:12:04 -0600 Vitamin D was once believed most critical for bone growth and overall bone health. Now researchers are suggesting that Vitamin D is vital also for new mothers and their unborn children. It is thought that Vitamin D is critical in maintaining the best immune system defenses throughout a normal healthy life. New disease risks have been found related to deficiencies or high amounts of Vitamin D. Vitamin D deficiencies are common among certain cultures and community. For instance, Vitamin D deficiencies are more prominent in people with darker skin. Rickets is a long time popular disease that occurs from extreme low levels of Vitamin D in infants or expectant mothers. It can be a popular disease, but it is easily preventable.http://www.onlinepharmacycr.com/products/rss/RSS/index61.htmlTue, 13 Jan 2009 09:11:50 -0600 When it comes to combating cancer, reach for broccoli most of all say researchers. The chemicals in cruciferous vegetables such as broccoli, cauliflower, and cabbage can help women effectively fight against the causes of cancer. While it has been openly known that eating these vegetables help your body fight against cancer, the mechanism for action has been primarily unknown. Now, researchers are confident that they have found the cause behind the anti-cancerous chemicals that are known to be in these vegetables. Researchers at UC Santa Barbara in biological studies have proven that the ultra beneficial substances in these vegetables work on the cellular level. Their findings have been officially published in the journal of Carcinogenesis.http://www.onlinepharmacycr.com/products/rss/RSS/index60.htmlTue, 13 Jan 2009 09:10:52 -0600 Cardiologists may have found a way to help cardiovascular surgery patients recover more quickly. The scientists have inserted a tiny pump through the groin and into the left ventricle of a patient. The pump will deliver five liters of blood per minute into the heart to assist the patient pump blood after surgery. Surgery takes a toll on mind and body, but it especially takes a hard toll on the heart which needs to recover from the invasive surgery. The device will help the heart and take a lot of the pressure on its recovered state and pump blood into the heart. This leaves the tissue to recover while still pumping blood as a vital function for life.http://www.onlinepharmacycr.com/products/rss/RSS/index59.htmlTue, 13 Jan 2009 09:10:51 -0600 A diminutive study shows that obesity surgery in teens can reverse diabetes, as it does in adults. In all but one of the 11 predominantly overweight teens studied, diabetes vanished within one year subsequent to weight-loss surgery, the researchers inform. The 11th patient still had diabetes, but needed much less insulin than prior to the surgery, and ceased taking diabetes pills. Prior research has demonstrated the diabetes advantages of obesity surgery for adults.http://www.onlinepharmacycr.com/products/rss/RSS/index58.htmlTue, 13 Jan 2009 09:10:18 -0600 Although there has been a battle waged against type 2 diabetes, recent data shows that Americans are actually losing the battle. Recent data has shown that the disease is sweeping across the nation with an estimated twenty four million Americans afflicted with the disease. These numbers are up by more than three million since last analyzed in the year 2005. Although diabetes type two can be controlled through medication, plenty of side effects cause irreversible damage. There is a wide range of complications that come with diabetes including heart disease, stroke, blindness, amputations, kidney disease, and nervous system damage. Continued research is being developed to combat these debilitating side effects. There are two separate ways doctors are trying to reverse the slow side effects that become eventually irreversible. http://www.onlinepharmacycr.com/products/rss/RSS/index57.htmlTue, 13 Jan 2009 09:07:25 -0600 Researchers continue to find ways to combat steroid resistant asthma. The researchers at Biomedical Forums have made it a priority to help patients with severe asthma. Asthma is a growing concern among the population with its rise in common occurrence. Steroid manufacturers have claimed that up to seventy percent of their product shipping is in asthma treatment costs. The biomedical researchers have said that finding suitable treatment for asthma sufferers continues to be a concern to help patients control symptoms and reduce the traumatic conditions. Researchers have started to focus on three main areas. 1. Track responsiveness to treatments and identify biomarkers of the asthma disease 2. Increase the responsiveness that patients are lacking to the treatments using steroids 3. Inform and further educate health care workers to use asthma treatments with steroids more properlyhttp://www.onlinepharmacycr.com/products/rss/RSS/index56.htmlTue, 13 Jan 2009 09:07:24 -0600 Scientists have succeeded in reversing brain birth defects in animal subjects, using stem cells to supercede faulty brain cells. Neural and behavioral birth imperfections, such as learning disabilities, are especially fastidious to treat, as collated to defects with known cause factors such as Parkinson's or Alzheimer's disease, because the prenatal teratogen acts diffusely in the fetal brain, ensuing in numerous imperfections. Scientists were able to surmount this impediment in laboratory tests with mice by using mouse embryonic neural stem cells.http://www.onlinepharmacycr.com/products/rss/RSS/index55.htmlTue, 13 Jan 2009 09:07:23 -0600 Scientists at Herbrew University in Jerusalem have reversed the debilitating brain birth defects through the use of stem cells in animals in the laboratory. The findings are expected to be announced and written in journals shortly for publishing. The announcement was made at a meeting for the International Society for Stem Cell Research in Barcelona, Spain. The brain birth defects targeted are neural and behavioral afflictions that appear first in the womb. Learning disabilities are especially hard to treat, and for people born with the affliction it can take years of therapy to help them become productive members of society. The scientists used stem cell research to reverse the defects which are more difficult to treat because of the prenatal teratogen.http://www.onlinepharmacycr.com/products/rss/RSS/index54.htmlTue, 13 Jan 2009 09:07:22 -0600 The Japan based pharmaceutical company, Sosei, has re-acquired its original rights to AD923 from Mundipharma International. Mundipharma had purchased rights from Sosei to commercialize AD923 across international markets excluding North America and Japan. Earlier this year, the drug reached Phase II clinical trials in Europe. Shortly after Phase II trials had begun, the company ran into a road block from the manufacturer of the device used to deliver the fentanyl spray. This caused trials to halt only a month after they had begun. A solution for the device has been created, but the company was unable to fund the continued trials and another investor was never found. The pharmaceutical company’s financial woes gave Sosei the ability to buy back rights, and it can now commercialize the product making revenue off the final medication. Sosei is not searching for another partner to continue the clinical trials and revitalize the research for AD923.http://www.onlinepharmacycr.com/products/rss/RSS/index53.htmlTue, 13 Jan 2009 09:07:21 -0600 SemBioSys Genetics who owns rights to plant produced recombinant human insulin has announced that MannKind, a pharmaceutical company, has bought the rights to license the product. The agreement gives the company the option to license until the end of March in 2009. The terms of the deal only allow MannKind to use the license for Afresa, MannKind’s fast acting insulin that had recently passed Phase III studies. The deal brought in an additional $2.5 million in revenue for SemBioSys Genetics. The money also includes an additional 2.4 million units of SemBioSys at a price per unit of $1. The purchase is expected to close in first quarter 2009. Each unit purchased by MannKind will give the company one common share of SemBioSys Genetics. The agreement also gives MannKind the option to purchase additional units for up to thirty six months following the deal.http://www.onlinepharmacycr.com/products/rss/RSS/index52.htmlTue, 13 Jan 2009 09:06:40 -0600 Researchers have developed a new gene therapy treatment that has regenerated some sight in a smattering of blind patients which have Leber’s Congenital Amaurosis, a condition in which, because of a missing or broken gene referred to as RPE65, retinal photoreceptor cells fail to operate within normal limits and ultimately die, leaving the individual blind. In completely freestanding research studies at the University of Pennsylvania and the University College London, researchers injected viral molecules containing a functioning facsimile of RPE65 into six patients’ retinas. The virus then transported the substitute gene into the retinal cell to replace the damaged or missing original cell.http://www.onlinepharmacycr.com/products/rss/RSS/index51.htmlTue, 13 Jan 2009 09:06:24 -0600 Schizophrenia and autism possibly share a common origin, Dutch researchers theorize after an expansive literature study. A developmental psychologist evinced that both mental diseases have very similar physical deviances which are formed during the first month of pregnancy. There has been exploration into whether there is a connection between the disorders in the first month of pregnancy and into the development of schizophrenia and autism. Curiously, many physical anomalies of autistics are also commonly discovered in schizophrenics. Both autistics and schizophrenic occasionally have protruding ears and idiosyncratic toes. There are also dissimilarities, such as a large head and intestinal issues, which are typical traits befalling autistics. From this, it has been deduced that the two disorders share a common origin. The same error that happens very early in pregnancy and becomes autism in one individual, can become schizophrenia in another.http://www.onlinepharmacycr.com/products/rss/RSS/index50.htmlTue, 13 Jan 2009 08:38:48 -0600 December 30, 2008 – Biovail Corporation, the makers of the pain killer Ultram, announced a voluntary recall of their Ultram ER 100mg tablets. The recall has come after Biovail realized that some of their tablets are about one percent with respect to dissolution at the eight hour mark. The minor issue should not affect patients, however, the pharmaceutical company has decided to take precautionary measures to ensure patient safety. Most importantly in the recall is that the cause of the recall has been identified and corrected. The cause for the recall stems from an excipients in the coating process during manufacturing of the pills. http://www.onlinepharmacycr.com/products/rss/RSS/index49.htmlTue, 13 Jan 2009 08:38:48 -0600 Ethex Corporation recalled lots of Hydromorphone pills in December 2008. The company announced that the lots may contain oversized pills in the shipped one hundred count bottles. Hydromorphone is a commonly used pain killer for many patients with moderate to severe pain. The recall protects patients from accidentally taking too much of the powerful pain killer.http://www.onlinepharmacycr.com/products/rss/RSS/index48.htmlTue, 13 Jan 2009 08:38:26 -0600 PriCara, a division of Ortho McNeil Janssen Pharmaceuticals, Inc has officially announced a recall on their Fentanyl patches. The C II patches are sold under the manufacturing name PriCara in the United States, but the 50 mcg/hr Fentanyl patches sold under the name of Sandoz Inc have also been recalled. The recall is completely voluntary as a preventative measure. Consumers are advised to return the patches to the pharmacy, and doctors and pharmacists are instructed to return the product to the manufacturer. The recall is in cooperation with the Federal Drug and Food Administration.http://www.onlinepharmacycr.com/products/rss/RSS/index47.htmlTue, 13 Jan 2009 08:38:47 -0600 It’s long been known that spending time outside has therapeutic effects for both the mind and the body. Spending time outside gives people a positive outlook mentally, and it can reduce stress and distract people from their pain from surgery. Researchers have recently confirmed that there are therapeutic effects in nature but more specifically for people who have recently started recovering from abdominal surgery. Researchers at Kansas State University have been studying the effects of plants and post operative patients and the benefits of nature on continued health. Plants have been used for mental health for centuries, but current research has also been using plants to provide drug therapies for people who suffer from diseases such as producing insulin for diabetic patients. The researchers have gathered and analyzed data for patients who have placed plants in hospital rooms after surgery for therapeutic effects.http://www.onlinepharmacycr.com/products/rss/RSS/index46.htmlTue, 13 Jan 2009 08:38:46 -0600 PharmaMar has some promising news for patients with lung cancer. PharmaMar has announced its intentions to begin Phase II trials of Irvalec, a treatment in the elimination of lung cancer tumors. The trials will be conducted with non-microcitic lung cancer and who have already been subjected to platinum based chemotherapy. Currently, lung cancer is the leading form of cancer that kills patients annually. While the term “lung cancer” is often used, it is a general term that envelopes a variety of cancers with unique growth patterns and cell formations. Each type of lung cancer requires different types of therapy that includes variations in chemotherapy, radiation treatments, and invasive surgeries.http://www.onlinepharmacycr.com/products/rss/RSS/index45.htmlTue, 13 Jan 2009 08:38:46 -0600 Can Fite BioPharma, an Israel based pharmaceutical company, has announced its new Phase II B rheumatoid arthritis trials for a new drug temporarily named CF101. The studies will involve 230 patients in a controlled environment. The patients are randomized and placed into three groups. The patients are then given doses of CF101 and a placebo. The patients were then asked to stick to treatment for twelve weeks and submit to a two week follow up to analyze progression. The new trials will be conducted across several different sites. Thirty different sites with variable amount of patients will be used across Europe and Israel.http://www.onlinepharmacycr.com/products/rss/RSS/index44.htmlTue, 13 Jan 2009 08:38:45 -0600 A new study suggests that people who eat a lot of iron from plant sources may have an elevated risk of Parkinson’s disease, particularly if their vitamin C consumption is lower than average. There is some indication for a correlation between iron intake, and/or environmental exposure to the metal, and Parkinson’s disease. Yet examinations of iron intake and Parkinson’s susceptibility have had diverse results, as has been notated in the American Journal of Epidemiology. To further analyze these findings a doctor and his colleagues from the University of Bari in Italy, anatomized data on 47,406 men and 79,947 women engaging in the Health Professionals Follow-Up Study. Between 1974 and 2000, 422 developed Parkinson’s.http://www.onlinepharmacycr.com/products/rss/RSS/index43.htmlTue, 13 Jan 2009 08:38:45 -0600 Researchers have recently discovered that a drug used to treat osteoporosis may leave the jaw vulnerable to necrosis. Fosomax is a commonly used drug that treats for osteoporosis in patients, but dental researchers fear it may cause bone tissue in the jaw to die. The study was conducted in the University of Southern California School of Dentistry. The results will be published in this month’s (January) Journal of the American Dental Association (JADA). Although Fosomax has been marketed as a leading osteoporosis medication, it also clearly stated up front that a side effect of bone degradation is possible. Researchers, however, feel that the occurrences of bone tissue necrosis are more than expected from a simple side effect and that the drug should be further studied as this side effect has increased their concern.http://www.onlinepharmacycr.com/products/rss/RSS/index42.htmlTue, 13 Jan 2009 08:38:44 -0600 Oncologists, originally determined to find therapies for colon cancer, have stumbled upon a treatment that may be effective against cancer in the eyes. The treatment focuses on starving tumors by limiting blood vessel growth which brings nutrients to the tumors and advocates cell proliferation. The discovery may help increase chances of stopping cancers in the eye and saving patients’ sight. The melanomas that affect millions of patients have been proven controllable by the new treatments. Usually, patients are subjected to a variety of radiation treatments but the hope to save sight is rare. Instead, patients are given a drug therapy called Avastin. It is a shot that is injected directly into the eye to help starve tumors from their vascular needs. The effects of limiting of the vascular are similar to starving a normal cell – the cell is inhibited from receiving detrimental nutrients so it eventually dies from lack of blood supply.http://www.onlinepharmacycr.com/products/rss/RSS/index41.htmlTue, 13 Jan 2009 08:38:44 -0600 AlphaVax, a North Carolina-based company, has sold the rights to an investigational vaccine it is developing for $20 million to Novartis, the multinational pharmaceutical company based in Basel, Switzerland. Novartis will also be expected to pay extra landmark fees and percentages, if the treatment with the experimental vaccine provides actual evidence of its effectiveness in clinical studies being conducted currently. The vaccine could even possibly prevent the development of cytomegalovirus (CMV), a familiar type of Herpes virus that can cause severe problems in individuals with already weakened immune systems, such as cancer patients, AIDS sufferers, and also newborn babies. "We are very happy to have the ability to gain access to such a promising vaccine contestant for the deterrence of cytomegalovirus infections," Andrin Oswald, CEO of Novartis' vaccines and diagnostics division, said with evident optimism.http://www.onlinepharmacycr.com/products/rss/RSS/index40.htmlTue, 13 Jan 2009 08:38:43 -0600 Crohn's disease is a disease most commonly diagnosed among 14 to 32 year-olds. However, there have been cases reported in older patients as well as young children. There is a seven to nine percent lifetime risk to develop the condition in children who have one parent with Crohn's disease They also have a ten percent chance to develop some type of inflammatory bowel disease. Children often experience symptoms without being diagnosed for a long time. Though researchers have not yet been able to discover the cure for Crohn's disease, there are many efficient medical and surgical treatments for the disease. For a person with Crohn's it is vital that he/she is having a good nutritious diet. It is also crucial to maintain a regular exercise regimen along with a positive attitude. http://www.onlinepharmacycr.com/products/rss/RSS/index39.htmlTue, 13 Jan 2009 08:38:42 -0600 Scientists at the prestigious Northwestern University have discovered that modern theories believing that vaginal walls can significantly reduce the transmission of HIV might not be accurate. Theories have been made that state HIV is too large to penetrate the tissue that aligns a woman’s vaginal tract. Recent studies at the University have shown that the HIV particles can in fact enter the tissue walls to a depth that gives them access to the target immune cells. For many years, the understanding of how HIV invades vaginal walls was deeply misunderstood. The researchers have developed formidable theories that help the scientific community better understand its method of infection. The Northwestern researchers in collaboration with Tulane University have discovered that the method of transmission is directly related to the level of shedding where cells are not so tightly integrated allowing the large HIV molecule to enter into the blood stream.http://www.onlinepharmacycr.com/products/rss/RSS/index38.htmlTue, 13 Jan 2009 08:38:42 -0600 Schizophrenia is not a well known disease, and for many sufferers it is a struggle to go through daily activities trying to understand your surroundings. Schizophrenics often have trouble reading other people. While this seems trivial to some people, the disease inhibits them from properly socializing with others. They are unable to properly read emotions and often misinterpret facial and emotional expressions as something other than the intention. Even the simplest of emotional communication is unknown to a typical schizophrenic. Schizophrenics are also immune to the simplest of responses from other people. While one person may exhibit a sad response, the schizophrenic is immune to the response. It makes the people around him consider the schizophrenic as uncaring and hard when in fact it is all typical of the disease. Typically, there is a schedule of drugs that are given to a diagnosed schizophrenic. http://www.onlinepharmacycr.com/products/rss/RSS/index37.htmlTue, 13 Jan 2009 08:38:41 -0600 Biomedical engineers have generated a new technique to discern colon cancer. A thin optical fiber that illuminates onto the interior of the colon. This method will be less invasive, and more comfortable for patients needing an already uncomfortable procedure. When colon cancer symptoms arise, the cancer is often already at an advance stage. To detect it early, frequent screening is a must. Soon, testing for colon cancer may not only be a whole lot simpler and more comfortable, but could also detect it earlier than ever before. Over 150,000 Americans will be diagnosed with colon cancer. That is a fact that worries many gastroenterologists, since only one half of the people who need a colonoscopy will get one. People often tend to steer clear of this invasive procedure, opting for ignorance over discomfort. While colonoscopies are an efficient means of detection, they are also quite invasive.http://www.onlinepharmacycr.com/products/rss/RSS/index36.htmlTue, 13 Jan 2009 08:38:40 -0600 For sufferers of Parkinson or Alzheimer, the depredating effects are unavoidable. There is not cure as relatives can simply watch their loved ones suffer with no cure. Researchers at Southern Methodist University and the University of Texas at Dallas have brought new hope in the form of protective compounds that coat the neurons. The compounds, they have found, protect the neurons that help slow their inevitable demise. The researchers’ original compounds constituted forty five chemicals that were tested for various conditions. After several tests were made, the researchers narrowed down the effective compounds to only four. The four compounds are shown to be potent protectors for neurons which are the main cells responsible for signals throughout your body for brain messages such as movement.http://www.onlinepharmacycr.com/products/rss/RSS/index35.htmlTue, 13 Jan 2009 08:38:40 -0600 New developments in gene therapy have developed ways of viewing genes in real time with a specialized industry camera. The new age techniques allow researchers to view gene expression in real time during activity. It would allow them to view cravings as they happen, and better understand love during its unique effects. The study is a new development in BMC Biotechnology that provides a view from above in a way for scientists to view gene expression while activities took place. The study has been conducted through the observation of small fruit flies. It gives new insight on the influence and behavior of expressed genes.http://www.onlinepharmacycr.com/products/rss/RSS/index34.htmlTue, 13 Jan 2009 08:38:39 -0600 King Pharmaceuticals, Inc has announced a new drug application to help cardiac patients who are unable to submit to a stress test. The drug, named Corvue (binodenoson) is a form of injection into patients using SPECT (single phone emission computed tomographic) to help diagnose risks of coronary arterial disease. The NDA is asking for the FDA to approve its new CorVue drug. It claims that it is non-invasive way to detect perfusion abnormalities that occur often in coronary arterial disease patients. The vasodilator has been proven, according to King, to be a selective agonist for adenosine A2A receptors. Currently, adenosine is the therapy of choice to use pharmacological stress testing.http://www.onlinepharmacycr.com/products/rss/RSS/index33.htmlTue, 13 Jan 2009 08:38:39 -0600 Researchers at Penn State's Hershey Medical Center and University Park have been studying nanoparticles as a therapeutic way to treat breast cancer. Nanoparticles, which are 1/5,000 in diameter to a human hair, has been shown to help kill melanoma and breast cancer cells in laboratory environments. The research comes as a huge leap in future enhancements to the anti-cancer research in ways to treat melanomas and breast cancer and replace the devastating effects of traditional chemotherapy. Like many researchers searching for the best answer to the debilitating disease, the researchers are hoping to introduce the drug as a new generation of anti-cancer therapy. Anti-cancer therapy has been called upon by patients who suffer from the painful side effects from chemotherapy. Chemotherapy has remained a staple in the lives of cancer patients who suffer nausea, loss of hair, extreme weight loss, and other life changing events.http://www.onlinepharmacycr.com/products/rss/RSS/index32.htmlTue, 13 Jan 2009 08:38:37 -0600 Early to bed, early to rise. It is a phrase with which most of us are familiar while growing up and being forced to wake up early. Now researchers say that an hour extra sleep may help reduce the risk of calcification in the arteries which is the first step towards developing cardiovascular disease. Researchers at the University of Chicago Medical Center have provided details in studies that show the benefits of extra sleep. They claim that their research proves the tiny amount of time can lower systolic pressure by 17 mm Hg. The studies were conducted with volunteers in the age range of forty and above. Of those people who were admitted into the study, twenty seven percent of patients who slept less than five hours a night developed calcifications. This number dropped significantly for those who slept a greater number of hours. Only eleven percent of patients who slept five to seven hours a night developed the hardening of the arterial walls and the numbers dropped even more for those who slept over seven hours a night. http://www.onlinepharmacycr.com/products/rss/RSS/index31.htmlTue, 13 Jan 2009 08:38:37 -0600 Researchers have created a catalog of diseases that helps other scientists cross reference the hundreds of tissue-specific disease. Breast cancer, Parkinsons, heart disease, and autism are just a few of the diseases researchers were able to put together in an easily readable for quick reference. The catalog is the first of its kind and it was published in the journal of Proceedings of the National Academy of Sciences. The catalog may lead to quicker and better understanding of drug therapy and disease. The catalog comes from a variety of sources to help understand how diseases work within specific tissues or organs. The interactions are cataloged to help scientists without the need for extensive study in live human subjects, which is of course not legal. The lack of proper research in laboratories on humans leaves a bottleneck for scientists whose focus is on drug therapies. The catalog will facilitate faster, more credible drugs to treat diseases.http://www.onlinepharmacycr.com/products/rss/RSS/index30.htmlTue, 13 Jan 2009 08:38:36 -0600 Researchers have been studying the use of topical microbicidal coating for use on damaged skin. They have found that using microbicidal coating on bandages applied to the skin kills most bacteria almost instantly and on contact. The coating is not just useful on bandages, but it is also highly useful for use on hospital gowns and bed sheets. It also protects hospital staff and other patients from acquiring bacterial infections while staying in patient recovery. This is a great benefit for health care officials since up to twenty thousand Americans get hospital infections every year. The study has a promising future for the many people who get sick from hospitals per year. It is reported that millions of Americans suffer from infections brought on from hospital visits every year. Researchers have been trying to limit these infections, so the microbicidal material has been developed to add to bandages to kill infectious bacteria on contact.http://www.onlinepharmacycr.com/products/rss/RSS/index29.htmlTue, 13 Jan 2009 08:38:35 -0600 Researchers at the Cornell University have recently discovered a link between the genes is the popular E.coli bacteria and inflammations in the intestinal tract of patients. The genes are also expressed in other diseases such as salmonella, cholera, and bubonic plague. Crohn’s disease is a common inflammatory disease that infects the lower, small intestines called the ileum. The disease is coming especially in North America where it occurs in one in one thousand patients. It has been long suspected that common gut bacteria, E.coli, played a role in the inflammation symptoms of Crohn’s disease. Although it has been suspected, the exact method of activity has been unknown to researchers of the disease. Cornell University scientists conducted a study that focused on sufferers of Crohn’s disease that focused on the ileum and colon. E.coli is easily cultured in the laboratory, so conducting the study was somewhat easily done. The culture was used to target specific subgroups of the bacteria for quantitative based characterization.http://www.onlinepharmacycr.com/products/rss/RSS/index28.htmlTue, 13 Jan 2009 08:38:35 -0600 LifeCycle Pharma has announced current enrollments in the Phase III clinical trials of their new drug therapy to help with patients who reject stable kidney transplants. LCP-Tacro has been undergoing tests by the pharmaceutical company as a preventative measure for liver or kidney transplants patients from rejecting the new tissue. The trials will begin with 300 kidney transplant patients in the program that span across the Unites States and Europe. The drug has been developed from a database of studies conducted on patients who rejected kidney and liver transplants. LCP-Tacro is a once-daily tablet that is taken to help patient’s bodies accept the new tissue without the life threatening possibilities of rejection. Although the study is focused on kidney transplant patients, the pharmaceutical company will continue talks with the Federal Drug Administration on trials conducted with liver transplant patients in the first quarter of 2009.http://www.onlinepharmacycr.com/products/rss/RSS/index27.htmlTue, 13 Jan 2009 08:38:34 -0600 King Pharmaceuticals initiated Phase II clinical trial programs for T-62, a tablet being tested for use in the treatment of neuropathic pain. The Phase II trials will be wide spread and will span across multiple laboratories and testing centers. The clinical tests will be randomized and double-blind methods will be utilized. The placebo controlled conditions will verify that patient’s conditions, side effects, and cures are not random coincidences and all theories can be reproduced. King Pharmaceuticals believe that the drug treatment will help patients with chronic postherpetic neuralgia pain.http://www.onlinepharmacycr.com/products/rss/RSS/index26.htmlTue, 13 Jan 2009 08:38:34 -0600 New ways of developing protein based drugs may help pharmaceutical companies develop better pills to treat a wide range of disease. Researchers in Michigan State University have design new ways to separate therapeutic agents from their growth byproducts. Protein drugs are often used in genetically modified Escherichia coli, a bacterium used in most research laboratories. The proteins fuse with the bacteria and they are separated from clumps of inclusion bodies. Although a widely used method of drug manufacturing, this process leaves about ninety five percent of the protein unusable. Creative methods have been introduced to help salvage some of the unused protein. Other methods break down the protein to separate it, but as most people know a protein’s determined function relies on its three dimensional shape. Breaking down proteins and having them remain functional means the proteins need to be refolded. This is not always feasible.http://www.onlinepharmacycr.com/products/rss/RSS/index25.htmlTue, 13 Jan 2009 08:38:33 -0600 ImmunoCellular Therapeutics (IMUC) has shown promising signs from data collected from clinical Phase I trials of ICT-107. ICT-107 is the company’s new dendritic cell based cancer vaccine. The vaccine is being studied as a viable agent to treat glioblastoma which is a malignant type of brain cancer. The pharmaceutical company’s data included no adverse side effects which prove the first phase of trials to be successful. The goal of the Phase I clinical trials for ICT-107 was to show that patients would have basic tolerability after therapy with the drug. Patients showed little sign of adverse side effects with was a promising stroke for IMUC. The trial was conducted with nineteen different patients at the Cedars Sinai Medical Center.http://www.onlinepharmacycr.com/products/rss/RSS/index24.htmlTue, 13 Jan 2009 08:38:33 -0600 Statistically, one in every twenty thousand eggs is contaminated with Salmonella bacteria. What does this mean for consumers? Drinking homemade eggnog can be a bit of a risk. Recently, however, researchers have been testing whether the alcohol inserted into spiked eggnog might help kill the deadly cells that can make humans incredibly ill. The researchers made a bit of a discovery – very few bacteria can survive a mixture of raw eggs and hard liquor such as twenty percent rum and bourbon. The researchers from the Rockefeller University provided test data that compared bacteria found in homemade alcoholic eggnog compared to the non-alcoholic eggnog normally found in grocery stores. After taking samples from each source and incubating the bacteria at twenty four to thirty seven degrees Celsius (body temperature) they found that the culture of homemade eggnog spiked with the alcohol was completely sterile.http://www.onlinepharmacycr.com/products/rss/RSS/index23.htmlTue, 13 Jan 2009 08:38:32 -0600 Researchers in the Unites States and China have discovered a unique way to kill leukemia cells. Grape seed extract has been shown in laboratories to kills leukemia cells by creating a “suicidal” effect. The grape seeds have been recently studied as a naturally effective way to kill cancer and it has been tested as a treatment without the use of drug therapies. The study was conducted by professors at the Graduate Center for Toxicology at the University of Kentucky. The results have been scheduled to be published in the January 2009 issue of Clinical Cancer Research. http://www.onlinepharmacycr.com/products/rss/RSS/index22.htmlTue, 13 Jan 2009 08:38:31 -0600 New levels of cancer treatment have been a call to action by many patients afflicted with cancer. Their collaboration is to help assist in progressing new cancer research and development. Together, they have developed ispinesib or SB-743921 that targets mitotic kinesins as a new way to treat the lethal disease. Ispinesib has been in initial Phase I and Phase II trials and it had been showing signs of promise for the two pharmaceutical companies. The seven year alliance between the two companies had proven productive for the future of pharmaceuticals. The two companies had developed three drug candidates in treating cancer patients. ispinesib or SB-743921 had become the golden child of the three as an anti-mitotic medication which slowed the development of new cancer cells in turn slowing proliferation of the disease.http://www.onlinepharmacycr.com/products/rss/RSS/index21.htmlTue, 13 Jan 2009 08:38:30 -0600 Researchers at the University of Michigan Health System have found a connection between a brain molecule and the elements of pain. The discovery is promising for patients who suffer from the elusive disease of fibromyalgia which is a pain crippling disease that is not well understood. Glutamate was found to directly contribute to patient pain. The study showed that as the molecule’s level went down pain was decreased in fibromyalgia patients. The discovery was found while searching for an effective drug therapy treatment for fibromyalgia patients. If the findings can be replicated in the laboratory then scientist may have doubled their research benefits by finding a cause and a solutions for fibromyalgia. Glutamate is a neurotransmitter which means it facilitates the messages in brain cells in the nervous system. Glutamate is released from one neuron as it travels to the next neuron and attaches to the cell receptor. This gives the brain a way to communicate between cells and it gives function to a variety of body mechanisms. Glutamate was suspected previously of being a component in the fibromyalgia disease since it was shown that glutamate receptors were highly excited in certain brain regions during pain episodes. Researchers used a form of acupuncture to mimic the therapy and study the brain waves of patients. Following four weeks of treatments, patients reported a significant lessening of pain. Even more interesting, the patients were shown to have less levels of glutamate in the insula. The more pain reduction reported the higher drop in glutamate levels was observed. The study brings a ray of hope for fibromyalgia patients, but further research is needed. Because of the small amount of patients studied, a higher level of research with more varied test subjects will need to be conducted before approval from the FDA.http://www.onlinepharmacycr.com/products/rss/RSS/index20.htmlTue, 13 Jan 2009 08:38:29 -0600 The Food and Drug Administration has approved a new drug on the market called Nexterone. Nexterone is an injection drug that is used for treatment and prophylaxis of frequent occurrances of ventricular fibrillation and unstable tachycardia. The drug was originally marketed under a different name in the United States by Wyeth as Cordarone Intravenous. The drug now offers treatment to patients with life threatening cardiac arrhythmias. It helps them manage their condition while limiting uncomfortable side effects. The product was introduced as a way to overcome solubility issues of amiodarone, one of the main components of heart drug therapy. The way researchers moved around the issue was by removing the cosolvents polysorbate 80 and benzyl alcohol. By removing these two components, Nexterone can be more effective for patients by removing the limitations regarding compatibility and stability with plastics and ionic infusion fluids. The benzyl alcohol removal also gives the drug more safety benefits since this component causes fatal gasping syndrome in newborn infants. The push for the new drug is also backed by the Joint Commission, the association responsible for accrediting hospitals. It is also backed by the Institute for Safe Medication Practices. The new drug is credited for providing health care workers with a safer, premixed formula to use on patients that limits the possibility of medication errors.http://www.onlinepharmacycr.com/products/rss/RSS/index19.htmlTue, 13 Jan 2009 08:38:26 -0600 The title itself seems ludicrous for most breast cancer patients. It has been a part of the central dogma of breast cancer that estrogen helps the disease proliferate further. New studies have shown, however, that new estrogen pills developed by Matthew Ellis, MB, PhD at the University School of Medicine in St. Louis has demonstrated a help in actually controlling metastatic breast cancer. Dr Ellis’ conducted studies on sixty six women who had developed a resistance against typical estrogen reducing therapies. Dr. Ellis was able to show that in one third of his sixty six participants, the cancerous tumors had stopped growing or even shrink subsequent to receiving a daily dose of estrogen. His funding came from the National Cancer Institute who received monies from the Avon Foundation.http://www.onlinepharmacycr.com/products/rss/RSS/index18.htmlTue, 13 Jan 2009 08:38:25 -0600 Dynavax Technologies announced in December 2008 of its termination in the collaboration with Merck & Co, Inc in the development of a Hepatitis B virus vaccine. HEPLISAV, the alliance’s Phase III vaccine, was produced from the two company’s research. All rights have been transferred to Dynavax that will continue to test and market the vaccine. Although the partnership has ended, Dynavax vowed to continue development of HEPLISAV in end-stage renal disease markets which it believes is approximately 70% of the market opportunity for the drug. If its findings for revenue and testing are found to be positive, it announced intentions to find a subsequent partner and investor to continue HEPLISAV’s development. Although the two big star pharmaceutical companies decided to split, Dynavax still maintains the drug’s superior results in clinical trials. Beginning 2009, the company expects to have a better understanding of the key pathways for HEPLISAV which is thought to help them find a better investor. Dynavax believes HEPLISAV is the next drug for the best future success to prevent infection of the Hepatitis B virus.http://www.onlinepharmacycr.com/products/rss/RSS/index17.htmlTue, 13 Jan 2009 08:38:24 -0600 Bacteria are the longest living creatures on the face of planet earth. It is no surprise that evolution has given bacteria defenses against host attack. Currently, bacteria have developed a wall around their cellular structure that helps it defend against human attack to rid the body from the cell’s invasion. The cell well made it difficult for researchers to study the inner molecular structure of the bacteria. Researchers at Rockefeller University have found a way to drill a small hole into the tough bacterial walls without destroying the cell leaving it unable to be studied. The study conducted by scientists in the Laboratory of Bacterial Pathogenesis and Immunology was able to prove findings by studying the advanced structure of the rapidly multiplying Streptococcus pyogenes. The bacterium is a highly infectious strain that contributes to a variety of diseases such as strep throat and rheumatic fever. Researchers were able to illicit bacterial functions by injecting an enzyme into cultures called sortase A. The enzyme attaches to the bacterial wall on protein antigens and gives the bacteria its well know infectious properties. By interfering with natural cell processes, researchers were able to render the bacteria benign. The enzyme strips the bacteria from its infectious outer wall rendering it useless. The approach is theoretically efficient on any gram positive bacteria such as strongly resistant bacteria such as Staphylococcus aureus and MRSA which are extremely resistant to even the best antibiotic treatments.http://www.onlinepharmacycr.com/products/rss/RSS/index16.htmlTue, 13 Jan 2009 08:38:21 -0600 Osteoarthritis is a debilitating disease that affects up to ten percent of the population. The disease starts with the disintegration of the articular cartilage that cushions joints between bone connections. The loss of cartilage leads to the disintegration of the bones causing bone spurs called osteophytes. It leads to an incredibly painful disease, and research scientists have been trying to design a drug to help people who suffer from osteoarthritis. Calcitonin is the natural hormone produced by the human thyroid gland. The important amino acid is responsible for increasing bone density and inhibiting the breakdown of bone tissue. Studies have recently been introduced that suggest that the drug may help the efforts of osteoarthritis patients to find a drug that will help relieve them from the disease. Calcitonin is normally used in nasal sprays, but it has recently been shown in female rats to help with the destruction of cartilage.http://www.onlinepharmacycr.com/products/rss/RSS/index15.htmlTue, 13 Jan 2009 08:38:19 -0600 People with a disorder that causes them to kick or cry out during deep sleep states are more likely than not to develop dementia or Parkinson's disease, a new Canadian study states. Researchers followed 93 REM Sleep Behavior Disorder patients and examined them after five, 10 and 12 years for signs of neurological disorders such as dementia or Parkinson's disease. After 12 years, researchers found that the majority of people with REM Sleep Behavior Disorder developed either dementia or Parkinson's, with 26 developing neurodegenerative disease, 15 developing Parkinsons and 11 developing some form of dementia.http://www.onlinepharmacycr.com/products/rss/RSS/index14.htmlTue, 13 Jan 2009 08:38:18 -0600 Eating fish is a common way for people to gain Omega 3 fatty acids that are reportedly healthy and nutritious. Farm raised tilapia, a white fish most highly consumed in America, has the lowest count in the beneficial acids says researchers in Wake Forest University School of Medicine. Making tilapia even worse is that it contains dangerously high levels of omega 6 fatty acids that make it a potentially hazardous combination. Although harmless for some people, the combination can be exceedingly dangerous for those with heart disease, arthritis, asthma and those allergic to exaggerated inflammatory responses such as those suffering from auto-immune diseases. The side effects of consuming too much tilapia can lead to inflammation of blood vessels, the heart, lungs, and joints. The effects are lethal in some highly sensitive individuals.http://www.onlinepharmacycr.com/products/rss/RSS/index13.htmlTue, 13 Jan 2009 08:38:17 -0600 Health care workers in emergency rooms are often carriers of the methicillin-resistant Staphylococcus aureus, possibly putting patients at risk, according to two reports recently published. Testing positive for MRSA is sometimes passing among health care workers. Unfortunately the results of this study, in conjunction with the results of the second report, compound distress that MRSA carriers are a prevalent part of the communication of MRSA among patients. Doctors collected nasal swabs from a instance of 105 emergency room staffers. Sixteen subjects tested positive for MRSA, including 12 nurses, 2 physicians, and 2 technicians. http://www.onlinepharmacycr.com/products/rss/RSS/index12.htmlTue, 13 Jan 2009 08:38:15 -0600 China Biologic Products has jumped into the International market with a new deal that will allow the plasma based pharmaceutical company the ability to brand its products in India. The total deal cost the company $1.6 million dollars, but it is the first deal made for the company to allow sales in other countries. Although drugs sold under the authorizations of the Central Drugs Standard Control Organization, the central location for drug authorization in India, sales have not been official until now. The products that are manufactured by the company for marketing are drug therapies focused on human hepatitis B Immunoglubulin for intravenal injection. The first shipment for China Biological Products has been ordered and the company is expected to start shipping in January of 2009. Their first shipment is expected to be close to a quarter of a million dollars. China Biological Products has created its own International sales department to help the company move further into more International markets with its products. The new move and agreement gives the company a way to compete with other pharmaceutical companies that are competitors with the newer pharmaceutical company.http://www.onlinepharmacycr.com/products/rss/RSS/index11.htmlTue, 13 Jan 2009 08:38:12 -0600 Celera and Abbott, two major front runners in the health care industry, have revised their alliance agreement. The agreement involves the distribution between the two companies. It gives Abbott the ability to distribute certain molecular diagnostic products that are manufactured by Celera. For many of the products like m2000 reagents, instruments, and other consumables Celera will receive royalties. For general genetic tests, Abbott will receive the royalties. Also included in the agreement is the collaboration of collection of royalties on future developments on the m2000 instrument. The agreement has a trial period of five years with the potential to continue the collaboration for an additional two years. The agreement also gives the two companies options to continue the renewal every two years if royalties continue to be promising. Some financial specifics were not openly disclosed to the public. The new revisions leave it open for both the companies to receive equal sharing in profits for products where Celera and Abbott have equal interests. It also gives both Celera and Abbott a more strategic way to commercialize products and forms an alliance for them to provide better testing and development of genetic products.http://www.onlinepharmacycr.com/products/rss/RSS/index10.htmlTue, 13 Jan 2009 08:37:18 -0600 A recent study corroborates that the regular awakenings from sleep that happen in heart failure patients with central sleep apnea (CSA) may show the occurance of another underlying waking disorder rather than being a defensive instrument to end apneas. Researchers involved in this study were surprised that using continuous positive airway pressure to assuage CSA had no effect on waking and no effect on sleep patterns. Findings denote that unlike obstructive sleep apnea, awakenings from sleep in CSA are not preventative, but probably have the opposite effect: they appear to be causative. This suggests that future studies should explore preventing stirring from sleep in order to treat CSA. Results show that after three months of treatment with continuous positive airway pressure (CPAP) therapy, heart failure patients with CSA show no meaningful improvement in the regularity of their waking or in their sleep patterns even though breathing pauses are significantly reduced by 55 percent from 35.4 central apneas and hypopneas per hour to 16.1 events per hour. Arousals remain high (24.3 arousals per hour on CPAP compared to 28.8 at baseline), total sleep time stays the same at 318 minutes, and sleep efficiency remains low at 70 percent.http://www.onlinepharmacycr.com/products/rss/RSS/index9.htmlMon, 12 Jan 2009 16:53:49 -0600 As we age, a slow chronic starvation to the brain triggers the reactions for Alzheimer’s disease, researchers say. Studies conducted at Northwestern University Feinberg School of Medicine found that aging plays a role in limiting sugar glucose. The process is thought to come from the aging cardiovascular disease and restriction of blood flow in the arteries. The restriction leads to clumps of proteins that were found to cause Alzheimer’s. Additionally, researchers found that a key brain protein is altered at the start of Alzheimer’s. The protein is altered specifically when a deficient supply of energy is sent to the brain. elF2alpha, when altered, flips on an enzyme that produces the sticky protein. The study was reproduced in laboratory conditions in human and mice brains. The study concludes that possible preventative measures for Alzheimer’s may involve increased oxygen and glucose levels to the brain. Exercise can help the cardiovascular system and increase oxygen to the brain and other organs. Researchers believe that exercise practiced in early years may help prevent the onslaught of Alzheimer’s disease.http://www.onlinepharmacycr.com/products/rss/RSS/index8.htmlMon, 12 Jan 2009 16:53:48 -0600 By utilizing a genome-wide affiliation for the first time to test for genes inculpate in high blood pressure, and studying both Amish and non-Amish people, US scientists have discovered a gene involved in governing how the kidneys process salt whose disparate they imply is linked to high blood pressure risk. High blood pressure is an tremendous public health worry, however very little is known about the genetic basis of this intricate condition. Approximately one quarter of Americans have high blood pressure. This puts them at an elevated risk of early death or diseases such as stroke and end-stage kidney disease. High blood pressure is typically treated with changes to diet and lifestyle plus medication like diuretics to help the kidneys remove Sodium ions (Na+) from the body. However, patients react differently to treatments, so recent studies may help to find out why.http://www.onlinepharmacycr.com/products/rss/RSS/index7.htmlMon, 12 Jan 2009 16:53:47 -0600 It has long been thought that patients develop autoimmune disease when they develop the cells that cannot determine self from foreign. Researchers have found, though, that even healthy patients have incidences of autoimmune cells even with a healthy medical background. Patients with autoimmune diseases like lupus and rheumatoid arthritis have cells that attack their own, healthy cells. The researchers have proven that even healthy people may carry these potent cells. The difference between a patient with an autoimmune disease and a healthy individual is that the healthy individual seems to have the same cells except they are set to an “off” position within the body. This may explain why the cells are completely harmless to the healthy individual. It is unknown if these cells are actually the precursors to the violent, killer autoimmune cells and it is unknown what prevents them from causing disease in some while remaining harmless in others. Autoimmune diseases are developed when antibody producing B cells are developed in the bone marrow.http://www.onlinepharmacycr.com/products/rss/RSS/index6.htmlMon, 12 Jan 2009 16:53:47 -0600 A major contributor to heart attacks and strokes is the narrowing of the arteries attributed to atherosclerosis. There has been confirmation regarding the relationship between low density lipoproteins and the enzyme ACAT2 which may point to a new way of treating the hardening of the arteries. Results have been reported that support a possible therapy for atherosclerosis by means of pharmaceutical inhibition of ACAT2. This study demonstrated that ACAT2 was critical to the development of atherosclerosis in rodents.http://www.onlinepharmacycr.com/products/rss/RSS/index5.htmlMon, 12 Jan 2009 16:53:41 -0600 New drug treatments for HIV infections have been underway to help the many HIV infected individuals throughout the world. Aptivus is a new treatment that uses the method of HIV-1 protease inhibitors. It inhibits the viral Gag and Gag-Pol polyproteins in HIV infected cells. The pathway, when inhibited, prevents the formation of mature virions that can form and infect subsequent cells. The new virus inhibitor has been used in patients who are familiar with anti-viral treatments. It is specifically used in combination with ritonavir with infected patients, both adults and adolescents, who are familiar with experimental ways to treat the virus and it is used with patients who have become resistant to more than one protease inhibitor.http://www.onlinepharmacycr.com/products/rss/RSS/index4.htmlMon, 12 Jan 2009 16:52:52 -0600 Exta-virgin olive oil might be the new trend in fighting off the spread and development of cancer. Chemicals called phytochemicals have been known to trigger cell death in cancer cells and it’s this chemical that is found in extra-virgin olive oil. The study came after trends in the diet industry where people who practice the Mediterranean Diet, a diet rich in oils, were less likely to develop breast cancer. Researchers in Spain set out to find the link between the oily diet and a reduction in the chance of cancer.http://www.onlinepharmacycr.com/products/rss/RSS/index3.htmlMon, 12 Jan 2009 16:51:10 -0600 Researchers have altered a primary protein that is responsible for promoting proper blood clotting. Their published results found in the Journal of Thrombosis and Haemostasis have promised opportunity in the treatment for hemophilia, the genetically inherited disease that causes excessive bleeding in almost thirty thousand Americans. Hemophiliacs lack an important protein, factor VIII, which is responsible to solidify and clot after breakage of the skin starts bleeding. The genetic engineering headed by researchers at the University of Rochester Medical Center have been studying the factor VIII protein and made slight alterations to its structure. The treatment is injected into patients who suffer from hemophilia, but in severe cases where the immune system has never seen the protein it attacks the treatment and renders it inactive. Normally, hemophiliacs spend in upwards of $200,000 in yearly costs to treat the disease.http://www.onlinepharmacycr.com/products/rss/RSS/index2.htmlMon, 12 Jan 2009 16:51:10 -0600 Allergen, the makers of Botox, has announced that they have been given approval from the Food and Drug Administration in the distribution of Latisse. Latisse is a new age drug treatment for patients with hypotrichosis of the eyelashes which basically means a patient has a poor amount of eyelash growth. The active component of Latisse, bimatroprost, is interestingly the same ingredient in the company’s other manufactured treatment for glaucoma. Lumigan was found to increase growth in patient’s eyelashes and it was listed as a side effect. The drug proved useful for further studies by Allergen to help aid patients with a lack of eyelash growth. Latisse is an easily applicable therapy that is applied to the base of the upper eyelash with sterile tools. Even after treatment has ceased, patients still have eyelashes return to normalcy.http://www.onlinepharmacycr.com/products/rss/RSS/index1.htmlMon, 12 Jan 2009 16:51:10 -0600